NeuroKinect is the study of movement related neurologic diseases. In order to evaluate the movement acuities, a revolutionary, non-wearable, low-cost 3D vision sensor is being used, the Kinect Sensor. The Kinect provides us several streams of information (i.e. color, depth, skeleton and infrared information) which are then used to 3D quantify the movement pattern of each individual.
NeuroKinect is being used to quantify:
- Epilepsy
- Parkinson’s Disease
- FAP (Paramiloidosis)
Epilepsy
Epileptic seizures are often accompanied by uncoordinated movement. From the clinicians perspective, uncoordinated seizure motion pattern of the patient’s body is considered as valuable evidence in the identification not only of the presence of a seizure but also its source.
- Cunha JPS, Choupina HMP, Rocha AP, Fernandes JM, Achilles F, Loesch AM, et al. (2016) NeuroKinect: A Novel Low-Cost 3Dvideo-EEG System for Epileptic Seizure Motion Quantification. PLoS ONE 11(1): e0145669. doi:10.1371/journal.pone.0145669 [h5-index:161-#4 Life Sciences&Earth Sciences; ISI impact factor: 3.234]
- Achilles, F., Choupina, H. M. P., Loesch, A. M., Cunha, J. P. S., Remi, J., Vollmar, C., … & Noachtar, S. (2016). EP 114. Uncovering epileptic seizures–A feasibility study for the semiological analysis of hidden patient motion during epileptic seizures. Clinical Neurophysiology, 127(9), e289.
- Rozanski V, Vollmar C, Cunha JPS, Tafula S, Ahmadi SA, et al. (2014) Connectivity patterns of pallidal DBS electrodes in focal dystonia: a diffusion tensor tractography study. Neuroimage 84: 435-442. [ISI impact factor: 6.252]
- Cunha JPS, Rémi J, Vollmar C, Fernandes JM, Gonzalez-Vitores JA, et al. (2013) Upper limb automatisms differ quantitatively in temporal and frontal lobe epilepsies. Epilepsy & Behavior 27: 404-408. [ISI impact factor: 1.844]
- Cunha JPS, Bento V, Paula LM, Dias E, Bilgin C, et al. (2012) Movement quantification in epileptic seizures: A feasibility study for a new 3D approach. Medical Engineering & Physics 34: 938-945. [ISI impact factor:1.779]
- Peters AS, Rémi J, Vollmar C, Gonzalez-Victores J, Cunha JPS, et al. (2011) Dysprosody during Epileptic Seizures Lateralizes to the Non-Dominant Hemisphere. Neurology 77: 1482-1486. [ISI impact factor: 8.176]
Parkinson’s Disease
Movement-related diseases, such as Parkinson’s disease (PD), affect progressively the motor function.
For that purpose, we present a RGB-D camera (Microsoft Kinect) system and its evaluation for PD assessment.
Key Papers:
- Cunha, J. P. S., Rocha, A. P., Choupina, H. M. P., Fernandes, J. M., Rosas, M. J., Vaz, R., … & Noachtar, S. (2016, October). A novel portable, low-cost kinect-based system for motion analysis in neurological diseases. In Engineering in Medicine and Biology Society (EMBC), 2016 IEEE 38th Annual International Conference of the (pp. 2339-2342). IEEE.
- Rocha, A. P., Choupina, H., Fernandes, J. M., Rosas, M. J., Vaz, R., & Cunha, J. P. S. (2015, August). Kinect v2 based system for Parkinson’s disease assessment. In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) (pp. 1279-1282). IEEE.
- Rosas, M. J., Cunha, J. P., Rocha, A., Choupina, H., Fernandes, J. M., & Vaz, R. (2015, June). Movement quantification for evaluation of gait in Parkinson’s disease using a RGB-D camera system. In MOVEMENT DISORDERS (Vol. 30, pp. S470-S471). 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY-BLACKWELL.
- Ana Patrícia Rocha, Hugo Choupina, José Maria Fernandes, Maria José Rosas, Rui Vaz, João Paulo Silva Cunha. “Parkinson’s Disease Assessment Based on Gait Analysis Using an Innovative RGB-D Camera System“. 36th Annual International IEEE EMBS Conference
- João Paulo Silva Cunha, Ana Patrícia Rocha, Hugo Choupina, José Maria Fernandes, Maria José Rosas, Rui Vaz. “Sistema de quantificação 3D de movimento porátil e de baixo custo para estimativa do sub-score de marcha em doentes parkinsónicos“. Sinapse no. 1 volume 14 (2014): 67.
FAP (Paramiloidosis)
Familial Amyloid Polyneuropathy (FAP) is a rare neurologic disease caused by an autosomal dominant genetic mutation that specially affects the peripheral nervous system.
The gait pattern of FAP patients is described as similar to the gait pattern of diabetic neuropathy, called steppage (pendent feet and bent knee), but it has never been quantified. This project aims at describing and quantifying the motor impairment of this population, focusing on gait.
Key Papers:
- C. Andrade, “A peculiar form of peripheral neuropathy – familial atypical generalized amyloidosis with special involvement of the peripheral nerves,” Brain, vol. 75, pp. 408-427, 1952.
- M. D. David Adams, Ph.D., “Recent advances in the treatment of familial amyloid polyneuropathy,” Ther Adv Neurol Disord, vol. 6, pp. 129 – 139, 2013.
Partners:
Funding: